About Me

I am Ph.D. candicate in Computer Science at Virginia Tech, advised by Professor Dawei Zhou. I received my M.S. in Biostatistics from the University of North Carolina at Chapel Hill in 2024, where I was luckily advised by Professor Yun Li, and my B.S. in Statistics from Zhejiang University in 2022 under the supervision of Professor Peng Zhang.

My research focuses on LLM Reasoning and Inference, with an emphasis on developing eliability, efficiency and principled evaluation frameworks for AI assurance. I am particularly interested in advancing the theoretical and empirical understanding of LLMs to improve their reliability and generalization in real-world applications.

What I'm Focusing

  • AI Assurance:

    Developed advanced methods to enhance large language models with robust adaptability and precision in open-world settings. [LensLLM, HalluGuard, Plan‑and‑Budget]

  • Ai4Science:

    Applied ML and statistical modeling to biological data for structure prediction, biomarker discovery, and disease analysis. [DISPROTBENCH, Epic-Unmix]

  • Exploring other areas and welcome collaborations!

Latest News

May 2026

Start as a researcher intern at Microsoft Copilot Frontier AI team. Honored to be invited for this opportunity to extend my research on test-time inference and hallucination control.

Apr 2026

Honored to receive Graduate Student Travel Fellowship by College of Engineering.

Mar 2026

Honored to receive Tier One Financial Travel Award by ICLR'26.

Feb 2026

Honored to be selected as Student Spotlight by Sanghani Center for AI & Data Analytics.

Feb 2026

Honored to be selected as one of twenty recipients of Travel Scholarship by ACM CAPWIC.

Jan 2026

My research about foundational LLM reasoning was accepted by ACM CAPWIC'26, see you in Alexandria on Mar 27-28!

Jan 2026

Two first-author papers (one leading-author: HalluGuard, one co-first: Plan-and-Budget) were accepted by ICLR'26! See you in Brazil this April!

Nov 2025

One paper Epic-Unmix was accepted by Genome Biology!

Aug 2025

My research about foundational LLM fine-tuning was accepted by ICDM'25 PhD forum, see you in D.C. on Nov 12-15!

Jul 2025

Honored to receive GPSS Travel Grant from Graduate School!

Jun 2025

Honored to receive Student Travel Award from CS Department!

May 2025

My first leading paper LensLLM has been accepted as poster at ICML'25 main conference!

Resume

Education

  1. Virginia Tech

    2023 — 2028

    College of Engineering
    PhD candidate in Computer Science

  2. University of North Carolina at Chapel Hill

    2022 — 2024

    Gillings School of Public Health
    Master of Science in Biostatistics

  3. Zhejiang University

    2018 — 2022

    School of Mathematical Sciences
    Bachelor of Science in Statistics

Experience

  1. Research Intern

    May 2026 — Aug 2026

    Microsoft, Redmond, USA

    • • Lead research on RL-based post-training and test-time search to improve the reliability and efficiency of LLMs in agentic Copilot systems, while designing and developing tool-augmented LLM agent pipelines in live environments to enable multi-LLM collaboration and long-horizon tool-use workflows.
  2. Graduate Research Assistant

    Aug 2024 — May 2028

    Computer Science, Virginia Tech, Blacksburg, USA

    • • Developed scalable methods to improve the reliability and efficiency of frontier AI systems, with a focus on hallucination mitigation, uncertainty quantification, and adaptive test-time efficiency—advancing the theoretical and empirical foundations of assured, efficient, and trustworthy large language models in real-world deployments.
  3. Visiting Scholar

    July 2023 — July 2024

    Computer Science, Virginia Tech, Blacksburg, USA

    • • Conducted research at the intersection of statistical learning theory and foundation models, developing principled probabilistic frameworks to characterize LLM generalization and reliability—laying the theoretical groundwork for subsequent work on model selection and uncertainty quantification.
  4. Graduate Research Assistant

    Aug 2022 — May 2024

    Biostatistics, UNC-Chapel Hill, Chapel Hill, USA

    • • Developed scalable Bayesian probabilistic frameworks and uncertainty-aware ML models for large-scale data inference, focusing on principled statistical learning methods with applications to heterogeneous, high-dimensional datasets.
  5. Student Researcher

    Oct 2019 — May 2024

    Statistics, Zhejiang University, Hangzhou, China

    • • Applied statistical optimization and deep learning to build state-of-the-art predictive systems in quantitative finance, developing end-to-end ML pipelines with measurable improvements in forecasting accuracy and computational efficiency.
  6. Software Design Engineer Intern

    July 2021 — Sep 2021

    Alibaba, Hangzhou, China

    • • Redesigned a legacy static-path system with a Java-based Dynamic Source Routing (DSR) algorithm incorporating a node-energy score, boosting end-to-end packet delivery from 88% to 97% and reducing average latency by 30% in 500-node stress tests under highly dynamic traffic.

Publications

Publications

  1. HalluGuard: Demystifying Data-Driven and Reasoning-Driven Hallucinations in LLMs

    2026

    Xinyue Zeng, Junhong Lin, Yujun Yan, Feng Gao, Liang Shi, Jun Wu, Dawei Zhou
    ICLR'26

  2. Plan and Budget: Effective and Efficient Test-Time Scaling on Large Language Model Reasoning

    2026

    Junhong Lin*, Xinyue Zeng*, Jie Zhu, Song Wang, Julian Shun, Jun Wu, Dawei Zhou (*Equal Contribution)
    ICLR'26

  3. LENSLLM: Unveiling Fine-Tuning Dynamics for LLM Selection

    2025

    Xinyue Zeng, Haohui Wang, Junhong Lin, Jun Wu, Tyler Cody, Dawei Zhou
    International Conference on Machine Learning (ICML) 2025

  4. DISPROTBENCH: A Disorder-Aware, Task-Rich Benchmark for Evaluating Protein Structure Prediction in Realistic Biological Contexts

    2025

    Xinyue Zeng, Tuo Wang, Adithya Kulkarni, Alexander Lu, Alexandra Ni, Phoebe Xing, Junhan Zhao, Siwei Chen, Dawei Zhou
    Preprint'25

  5. DiagnoLLM: A Hybrid Bayesian Neural Language Framework for Interpretable Disease Diagnosis

    2025

    Bowen Xu*, Xinyue Zeng*, Jiazhen Hu, Tuo Wang, Adithya Kulkarni (*Equal Contribution)
    Preprint'25

  6. Scientific Hypothesis Generation and Validation: Methods, Datasets, and Future Directions

    2025

    Adithya Kulkarni, Fatimah Alotaibi, Xinyue Zeng, Longfeng Wu, Tong Zeng, Barry Menglong Yao, Minqian Liu, Shuaicheng Zhang, Lifu Huang, Dawei Zhou

  7. Cell-type specific inference from bulk RNA-sequencing data by integrating single cell reference profiles via EPIC-unmix

    2024

    Chenwei Tang, Quan Sun, Xinyue Zeng, Xiaoyu Yang, Fei Liu, Jinying Zhao, Yin Shen, Bixiang Liu, Jia Wen, Yun Li
    Genome Biology

  8. Development of stock investment system based on big data analysis and statistical optimization

    2022

    Xinyue Zeng, Yuting Fu, Haiyun Zou, Peng Zhang
    National Innovation and Entrepreneurship Program at Zhejiang University

Portfolio

Awards & Honors

  1. Tier One Financial Travel Award

    2025 — 2026

    ICLR'26

  2. Graduate Student Travel Fellowship

    2025 — 2026

    College of Engineering

  3. Student Spotlight

    2025 — 2026

    Sanghani Center for AI & Data Analytics

  4. Sanghani Center Travel Grant

    2025 — 2026

    Sanghani Center for AI & Data Analytics

  5. Travel Scholarship

    2025 — 2026

    ACM CAPWIC

  6. GPSS Travel Grant

    2024 — 2025

    Virginia Tech Graduate School

  7. CS Travel Award

    2024 — 2025

    Virginia Tech CS Department

  8. Biostatistics Travel Award

    2023 — 2024

    UNC-Chapel Hill

  9. Undergraduate Innovation and Entrepreneurship Award

    2021 — 2022

    Zhejiang University

Presentations

  1. HalluGuard: Demystifying Data-Driven and Reasoning-Driven Hallucinations in LLMs

    2026

    Fourteenth International Conference on Learning Representations(ICLR 2026)

  2. Plan and Budget: Effective and Efficient Test-Time Scaling on Large Language Model Reasoning

    2026

    Fourteenth International Conference on Learning Representations(ICLR 2026)

  3. Foundational LLM Reasoning and Inference

    2026

    ACM CAPWIC 2026

  4. Foundational LLM Fine-tuning

    2025

    International Conference on Data Mining (ICDM) PhD Forum 2025

  5. LENSLLM: Unveiling Fine-Tuning Dynamics for LLM Selection

    2025

    Forty-Second International Conference on Machine Learning (ICML 2025)

  6. Gaussian-Process-Based Cell Type Specific Unmixing of Bulk Expression Profiles

    2024

    ENAR 2024 Spring Meeting

  7. Wildlife recognition based on deep learning

    2022

    Dissertation Defense for Undergraduate Thesis at Zhejiang University

Invited Talks

  1. Invited Talk for HalluGuard

    Apr 2026

    NICE AI

  2. Invited Talk for LensLLM

    Oct 2025

    Cerebras AI

  3. Invited Talk for LensLLM

    Oct 2025

    PLOUTOS AI

  4. Guest Lecture: CS 4824

    March 2025

    Virginia Tech

Services

  1. Reviewer

    ICLR 2026, ICLR 2026 workshop, ICML 2026(Golden Reviewer), KDD 2026, NeurIPS 2026

Copyrights

  1. Statistical Analysis Platform

    2023

    Software Copyright in China

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